Measuring the impact of Ebola control measures in Sierra Leone.
نویسندگان
چکیده
Between September 2014 and February 2015, the number of Ebola virus disease (EVD) cases reported in Sierra Leone declined in many districts. During this period, a major international response was put in place, with thousands of treatment beds introduced alongside other infection control measures. However, assessing the impact of the response is challenging, as several factors could have influenced the decline in infections, including behavior changes and other community interventions. We developed a mathematical model of EVD transmission, and measured how transmission changed over time in the 12 districts of Sierra Leone with sustained transmission between June 2014 and February 2015. We used the model to estimate how many cases were averted as a result of the introduction of additional treatment beds in each area. Examining epidemic dynamics at the district level, we estimated that 56,600 (95% credible interval: 48,300-84,500) Ebola cases (both reported and unreported) were averted in Sierra Leone up to February 2, 2015 as a direct result of additional treatment beds being introduced. We also found that if beds had been introduced 1 month earlier, a further 12,500 cases could have been averted. Our results suggest the unprecedented local and international response led to a substantial decline in EVD transmission during 2014-2015. In particular, the introduction of beds had a direct impact on reducing EVD cases in Sierra Leone, although the effect varied considerably between districts.
منابع مشابه
Mining and Environmental Degradation: a Gift Brings Grief Scenario for Mining Communities in Sierra Leone
Sierra Leone is blessed with abundant natural resources but yet prone to environmental degradation due to the mining operations. Most often, the mining communities are faced with social tensions, as a result of the possible trade-off between the expected employment impact and the cost of mining operations to the environment. Over the past decades, the contribution of the mining sector to the de...
متن کاملEconomic policy – Public health linkage and the importance of a regional platform: The case of tobacco control
Ezeh A (2015) Leadership and health in Africa, perspectives. The Lancet 385. Available at: http:// www.thelancet.com/pdfs/journals/lancet/PIIS01406736(15)61010-8.pdf The World Bank (2015) Ebola: Most African Countries Avoid Major Economic Loss but Impact on Guinea, Liberia, Sierra Leone Remains Crippling. Available at: https://www.worldbank. org/en/news/press-release/2015/01/20/ebola-most-afric...
متن کاملRapid Assessment of Ebola Infection Prevention and Control Needs — Six Districts, Sierra Leone, October 2014
As of October 31, 2014, the Sierra Leone Ministry of Health and Sanitation had reported 3,854 laboratory-confirmed cases of Ebola virus disease (Ebola) since the outbreak began in May 2014; 199 (5.2%) of these cases were among health care workers. Ebola infection prevention and control (IPC) measures are essential to interrupt Ebola virus transmission and protect the health workforce, a populat...
متن کاملComparison of social resistance to Ebola response in Sierra Leone and Guinea suggests explanations lie in political configurations not culture
Sierra Leone and Guinea share broadly similar cultural worlds, straddling the societies of the Upper Guinea Coast with Islamic West Africa. There was, however, a notable difference in their reactions to the Ebola epidemic. As the epidemic spread in Guinea, acts of violent or everyday resistance to outbreak control measures repeatedly followed, undermining public health attempts to contain the c...
متن کاملEbola wreaks havoc in Sierra Leone
BACKGROUND Ebola virus disease has taken a toll on more than 8,000 lives in West Africa in 2014. The most affected countries are Guinea, Liberia, and Sierra Leone. The number of people infected by Ebola in Sierra Leone surpassed that of Liberia in the last month in this year and almost half of human cases are distributed in this country. DISCUSSION The ignorance on Ebola among people, includi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 112 46 شماره
صفحات -
تاریخ انتشار 2015